{"id":2785,"date":"2014-10-09T04:45:24","date_gmt":"2014-10-09T08:45:24","guid":{"rendered":"https:\/\/www.huntermoyermd.com\/?p=2785"},"modified":"2020-05-04T12:51:19","modified_gmt":"2020-05-04T12:51:19","slug":"the-history-of-botox-cosmetic","status":"publish","type":"post","link":"https:\/\/www.huntermoyermd.com\/blog\/the-history-of-botox-cosmetic\/","title":{"rendered":"The History of Botox\u00ae Cosmetic"},"content":{"rendered":"<p>No one can argue that the use of Botox\u00ae cosmetic to help alleviate the signs of facial aging has become incredibly popular.\u00a0 In 2013 alone, over 6.3 million treatments were preformed in the United States with Botulinum Toxin Type A, the active ingredient in cosmetic injectables like Botox\u00ae and Dysport\u00ae, and that number continues to rise every year.\u00a0 However, despite its incredible popularity, many don\u2019t know the fascinating history behind the development of this extremely versatile <a title=\"facial rejuvenation procedure\" href=\"https:\/\/www.huntermoyermd.com\/face\/\">facial rejuvenation procedure<\/a>.<\/p>\n<p><b>1820\u2019s<\/b> \u2013 Dr. Justinus Kerner studies a batch of improperly prepared blood sausages responsible for the death of several dozen Germans.\u00a0 His experiments lead to a better understanding of the neurological symptoms of food-borne botulism (drooping eyelids, difficulty swallowing, muscle weakness, and if left untreated, paralysis and respiratory failure).<\/p>\n<p><b>1890\u2019s<\/b> \u2013 While investigating an outbreak of botulism, Dr. Emile Pierre van Ermengem of Belgium is able to make a connection between botulism and a spore-forming bacterium he named Bacillus botulinus (later renamed Clostridium botulinum).<\/p>\n<p><b>1953<\/b> \u2013 Physiologist Dr. Vernon Brooks discovers that injecting small amounts of botulinum toxin into a hyperactive muscle blocks the release of acetylcholine from motor nerve endings, causing temporary \u201crelaxation\u201d and reducing involuntary muscle spasms.<\/p>\n<p><b>1978<\/b> \u2013 After several years of injecting botulinum toxin type A into monkeys in an attempt to discover if its muscle relaxing effects might help in the treatment of strabismus, or crossed eyes, Dr. Alan B. Scott receives FDA approval to inject tiny amounts of botulinum toxin into human volunteers.<\/p>\n<p><b>1988<\/b> \u2013 The pharmaceutical company Allergan Inc. acquires the rights to distribute Scott\u2019s batch of botulinum toxin type A, and begins conducting additional research.\u00a0 Eventually, it is discovered that the drug can also provide patients with temporary relief from facial spasms, neck and shoulder spasms, and even vocal cord spasms.<\/p>\n<p><b>1989<\/b> \u2013 The FDA approves botulinum toxin type A for the treatment of both strabismus (crossed eyes) and blepharospasm (spasms of the eyelid muscle).\u00a0 Allergan introduces it to the market under the brand name <a title=\"Botox\u00ae Cosmetic\" href=\"https:\/\/www.huntermoyermd.com\/botox\/\">Botox\u00ae Cosmetic<\/a>.<\/p>\n<p><b>1992<\/b> \u2013 After noticing that her blepharospasm patients were starting to lose their frown lines, Canadian ophthalmologist Dr. Jean Carruthers, and her dermatologist husband, publishes a study in the Journal of Dermatologic Surgery and Oncology stating that though temporary, \u201ctreatment with C. botulinum-A exotoxin is a simple, safe procedure\u201d for the treatment of brow wrinkles.<\/p>\n<p><b>1997<\/b> \u2013 Botox\u00ae use increases so rapidly that the country\u2019s supply is temporary exhausted until a new batch receives FDA approval.<\/p>\n<p><b>2002<\/b> \u2013 FDA approves Botox\u00ae\u00a0Cosmetic (onabotulinumtoxinA), the same formulation as Botox\u00ae, for use in alleviating moderate to severe frown lines between the eye brows.<\/p>\n<p><b>2004<\/b> \u2013 FDA approves Botox\u00ae\u00a0for the treatment of severe underarm sweating that does not respond well to topical medicines.<\/p>\n<p><b>2006<\/b> \u2013 Botox\u00ae sales soar past the $1 billion mark, with cosmetic uses accounting for about half of sales.<\/p>\n<p><b>2010<\/b> \u2013 FDA approves Botox\u00ae\u00a0therapy for increased muscle stiffness in elbow, wrist, and finger muscles with upper limb spasticity.\u00a0\u00a0 Later that year, Botox\u00ae\u00a0becomes the first medicine to be approved by the FDA specifically for the prevention of headaches in adults who suffer from chronic migraines.<\/p>\n<p><b>2014<\/b> \u2013 Botox\u00ae Cosmetic receives FDA approval for the temporary treatment of moderate to severe crow\u2019s feet, also known as lateral canthal lines.<\/p>\n<p>If you have any questions about Botox\u00ae cosmetic or are interested in any of the treatments that I offer, please <a title=\"contact us\" href=\"https:\/\/www.huntermoyermd.com\/contact\/\">contact us<\/a> today to schedule a consultation.\u00a0 Additionally, Atlanta Plastic Surgery, P.C. provides a variety of options for financing, including Care Credit\u00ae, to assist you.\u00a0 Don\u2019t forget to connect with me, <a title=\"Dr. Hunter Moyer\" href=\"https:\/\/www.huntermoyermd.com\/about\/\">Dr. Hunter Moyer<\/a>, on <a href=\"https:\/\/www.facebook.com\/huntermoyermd\" target=\"_blank\" rel=\"noopener noreferrer\">Facebook<\/a>, <a href=\"https:\/\/twitter.com\/HunterMoyerMD\" target=\"_blank\" rel=\"noopener noreferrer\">Twitter<\/a>, and <a href=\"https:\/\/plus.google.com\/+Huntermoyermd\/posts\" target=\"_blank\" rel=\"noopener noreferrer\">Google+<\/a> for the latest plastic surgery news.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>No one can argue that the use of Botox\u00ae cosmetic to help alleviate the signs of facial aging has become incredibly popular.\u00a0 In 2013 alone, over 6.3 million treatments were preformed in the United States with Botulinum Toxin Type A, the active ingredient in cosmetic injectables like Botox\u00ae and Dysport\u00ae, and that number continues to &hellip; <a href=\"https:\/\/www.huntermoyermd.com\/blog\/the-history-of-botox-cosmetic\/\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[408,357,375,1],"tags":[402,354,236,415,264,435,436,437],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/posts\/2785"}],"collection":[{"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/comments?post=2785"}],"version-history":[{"count":1,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/posts\/2785\/revisions"}],"predecessor-version":[{"id":3416,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/posts\/2785\/revisions\/3416"}],"wp:attachment":[{"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/media?parent=2785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/categories?post=2785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.huntermoyermd.com\/blog\/wp-json\/wp\/v2\/tags?post=2785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}